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2.5-star hotel Pet friendly

Best Western Plus Sikeston I-55

120 S Interstate Drive, Sikeston, MO
4.2
Very good 1,002 guest reviews
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1 King Bed Microwave and Refrigerator Work Desk WiFi Full Breakfast (1 of 16)
1 King Bed Microwave and Refrigerator Work Desk WiFi Full Breakfast (2 of 16)
1 King Bed Microwave and Refrigerator Work Desk WiFi Full Breakfast (3 of 16)
1 King Bed Microwave and Refrigerator Work Desk WiFi Full Breakfast (4 of 16)
1 King Bed Microwave and Refrigerator Work Desk WiFi Full Breakfast (5 of 16)
1 King Bed Microwave and Refrigerator Work Desk WiFi Full Breakfast (6 of 16)
1 King Bed Microwave and Refrigerator Work Desk WiFi Full Breakfast (7 of 16)
1 King Bed Microwave and Refrigerator Work Desk WiFi Full Breakfast (8 of 16)
1 King Bed Microwave and Refrigerator Work Desk WiFi Full Breakfast (9 of 16)
1 King Bed Microwave and Refrigerator Work Desk WiFi Full Breakfast (10 of 16)
1 King Bed Microwave and Refrigerator Work Desk WiFi Full Breakfast (11 of 16)
1 King Bed Microwave and Refrigerator Work Desk WiFi Full Breakfast (12 of 16)
1 King Bed Microwave and Refrigerator Work Desk WiFi Full Breakfast (13 of 16)
1 King Bed Microwave and Refrigerator Work Desk WiFi Full Breakfast (14 of 16)
1 King Bed Microwave and Refrigerator Work Desk WiFi Full Breakfast (15 of 16)
1 King Bed Microwave and Refrigerator Work Desk WiFi Full Breakfast (16 of 16)
16 photos

1 King Bed Microwave and Refrigerator Work Desk WiFi Full Breakfast

king
  • Today's low rate
Rate needs datesTotals change by night
Standard rate
Accessible 1 King Mobility Accessible Bathtub Work Desk Microwave and Refrigerator WiFi Full Breakfast (1 of 16)
Accessible 1 King Mobility Accessible Bathtub Work Desk Microwave and Refrigerator WiFi Full Breakfast (2 of 16)
Accessible 1 King Mobility Accessible Bathtub Work Desk Microwave and Refrigerator WiFi Full Breakfast (3 of 16)
Accessible 1 King Mobility Accessible Bathtub Work Desk Microwave and Refrigerator WiFi Full Breakfast (4 of 16)
Accessible 1 King Mobility Accessible Bathtub Work Desk Microwave and Refrigerator WiFi Full Breakfast (5 of 16)
Accessible 1 King Mobility Accessible Bathtub Work Desk Microwave and Refrigerator WiFi Full Breakfast (6 of 16)
Accessible 1 King Mobility Accessible Bathtub Work Desk Microwave and Refrigerator WiFi Full Breakfast (7 of 16)
Accessible 1 King Mobility Accessible Bathtub Work Desk Microwave and Refrigerator WiFi Full Breakfast (8 of 16)
Accessible 1 King Mobility Accessible Bathtub Work Desk Microwave and Refrigerator WiFi Full Breakfast (9 of 16)
Accessible 1 King Mobility Accessible Bathtub Work Desk Microwave and Refrigerator WiFi Full Breakfast (10 of 16)
Accessible 1 King Mobility Accessible Bathtub Work Desk Microwave and Refrigerator WiFi Full Breakfast (11 of 16)
Accessible 1 King Mobility Accessible Bathtub Work Desk Microwave and Refrigerator WiFi Full Breakfast (12 of 16)
Accessible 1 King Mobility Accessible Bathtub Work Desk Microwave and Refrigerator WiFi Full Breakfast (13 of 16)
Accessible 1 King Mobility Accessible Bathtub Work Desk Microwave and Refrigerator WiFi Full Breakfast (14 of 16)
Accessible 1 King Mobility Accessible Bathtub Work Desk Microwave and Refrigerator WiFi Full Breakfast (15 of 16)
Accessible 1 King Mobility Accessible Bathtub Work Desk Microwave and Refrigerator WiFi Full Breakfast (16 of 16)
16 photos

Accessible 1 King Mobility Accessible Bathtub Work Desk Microwave and Refrigerator WiFi Full Breakfast

king
Rate needs datesTotals change by night
Standard rate
2 Queen Beds Microwave and Refrigerator Work Desk WiFi Full Breakfast (1 of 7)
2 Queen Beds Microwave and Refrigerator Work Desk WiFi Full Breakfast (2 of 7)
2 Queen Beds Microwave and Refrigerator Work Desk WiFi Full Breakfast (3 of 7)
2 Queen Beds Microwave and Refrigerator Work Desk WiFi Full Breakfast (4 of 7)
2 Queen Beds Microwave and Refrigerator Work Desk WiFi Full Breakfast (5 of 7)
2 Queen Beds Microwave and Refrigerator Work Desk WiFi Full Breakfast (6 of 7)
2 Queen Beds Microwave and Refrigerator Work Desk WiFi Full Breakfast (7 of 7)
7 photos

2 Queen Beds Microwave and Refrigerator Work Desk WiFi Full Breakfast

queen
Rate needs datesTotals change by night
Standard rate
1 King Bed Bathtub Accessible (1 of 16)
1 King Bed Bathtub Accessible (2 of 16)
1 King Bed Bathtub Accessible (3 of 16)
1 King Bed Bathtub Accessible (4 of 16)
1 King Bed Bathtub Accessible (5 of 16)
1 King Bed Bathtub Accessible (6 of 16)
1 King Bed Bathtub Accessible (7 of 16)
1 King Bed Bathtub Accessible (8 of 16)
1 King Bed Bathtub Accessible (9 of 16)
1 King Bed Bathtub Accessible (10 of 16)
1 King Bed Bathtub Accessible (11 of 16)
1 King Bed Bathtub Accessible (12 of 16)
1 King Bed Bathtub Accessible (13 of 16)
1 King Bed Bathtub Accessible (14 of 16)
1 King Bed Bathtub Accessible (15 of 16)
1 King Bed Bathtub Accessible (16 of 16)
16 photos

1 King Bed Bathtub Accessible

king
  • Free cancellation
Rate needs datesTotals change by night
Standard rate
1 King Bed (1 of 16)
1 King Bed (2 of 16)
1 King Bed (3 of 16)
1 King Bed (4 of 16)
1 King Bed (5 of 16)
1 King Bed (6 of 16)
1 King Bed (7 of 16)
1 King Bed (8 of 16)
1 King Bed (9 of 16)
1 King Bed (10 of 16)
1 King Bed (11 of 16)
1 King Bed (12 of 16)
1 King Bed (13 of 16)
1 King Bed (14 of 16)
1 King Bed (15 of 16)
1 King Bed (16 of 16)
16 photos

1 King Bed

king
  • Free cancellation
Rate needs datesTotals change by night
Standard rate

Double Accessible King Size Bed

double
Rate needs datesTotals change by night
No dates yetRecently from $131 / night
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Where you'll be in Sikeston, MO

120 S Interstate Drive, Sikeston, MO · 37.2 mi from Cape Girardeau Regional Airport (CGI)

Nearby

Cape Girardeau Regional Airport (CGI)
37.2 mi

What's included

All 39 amenities

Property Services

  • Shopping on site
  • Express check-out
  • Water dispenser
  • 24-hour front desk
  • Laundry facilities
  • Professional property host/manager

Parking & Transport

  • Uncovered parking
  • Free RV, bus, truck parking
  • Free self parking

Accessibility

  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible van parking
  • Wheelchair-accessible path to elevator
  • Wheelchair-accessible registration desk
  • Wheelchair-accessible fitness center
  • Well-lit path to entrance
  • Braille or raised signage
  • Stair-free path to entrance
  • Wheelchair accessible parking
  • Stairwell handrail height (inches) - 34
  • No accessible shuttle
  • Stairwell handrail height (centimeters) - 86
  • Handrails in stairways
  • Number of accessible parking spaces - 3
  • Elevator
  • Wheelchair accessible path of travel

Food & Drink

  • Free full breakfast
  • Free breakfast

Pool & Spa

  • Swimming pool
  • Number of indoor pools - 1

Internet

  • Free WiFi
  • Internet access in public areas - high speed

Business

  • Business center
  • Computer station
  • 24-hour business center

Policies

  • Smoke-free property

Things to Do

  • Fitness facilities

Pets

  • Service animals are allowed
  • Service animals are exempt from fees/restrictions
  • Pets allowed

Property details

Check-in3:00 PM - anytime
Check-out11:00 AM
About Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55 is a 2.5-star hotel in Sikeston, Missouri, positioned off Interstate 55 for convenient highway access. The property provides standard lodging amenities including a free breakfast, fitness center, business center, and 24-hour front desk service. Laundry facilities are available for guests needing extended-stay conveniences.

The hotel sits within walking distance of City of Miner Convention Center and a short drive from Sikeston Depot Museum, offering easy access to local attractions. Cape Girardeau Regional Airport lies approximately 30 minutes away, making the location practical for business and leisure travelers arriving by air.

Best Western Plus Sikeston I-55 serves as a straightforward base for visitors attending conventions, exploring area history, or passing through on I-55 corridor travel.

Guest rating breakdown
Cleanliness 4.2
Comfort 4.2
Service 4.4
Condition 4.0
Amenities 4.1
Neighborhood 4.2
Fees and extras
  • Fee for in-room wireless internet: USD 1 per stay (rates may vary) Pet fee: USD 25.00 per pet, per night Service animals are exempt from fees Rollaway bed fee: USD 10.0 per stay The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.
Check-in instructions
  • Extra-person charges may apply and vary depending on property policy
  • Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
  • Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
  • This property accepts credit cards; cash is not accepted
  • Safety features at this property include a fire extinguisher
  • This property affirms that it follows the cleaning and disinfection practices of We Care Clean (Best Western)
  • Front desk staff will greet guests on arrival at the property. Information provided by the property may be translated using automated translation tools.
Pet policy
  • Pets allowed based on the availability of pet friendly rooms. Up to 2 dogs per room with a 80 pound weight limit. Additional pet types (cats, birds, etc) may be accepted at the hotelâ??s discretion. Pet rate is $20.00 per day.
Know before you go
  • Guests can arrange to bring pets by contacting the property directly, using the contact information on the booking confirmation (surcharges apply and can be found in the Fees section).
  • For details on Best Western's privacy policy, visit www.bestwestern.com/privacy .

Frequently asked questions

What are the check-in and check-out times?
Check-in starts at 3:00 PM - anytime. Check-out is by 11:00 AM.
Are taxes and fees included in the price?
Yes. Every total shown includes taxes and fees, and we never add a booking fee. Resort fees, where a hotel charges them, are collected at the property.
Can I cancel my booking?
Free cancellation is available on at least one rate for these dates. Each room card says whether that rate includes it before you book.
Is Best Western Plus Sikeston I-55 pet-friendly?
Yes — this property accepts pets. Charges and restrictions vary, so check the pet policy under Property details or call us before you book.
How far is the airport?
Cape Girardeau Regional Airport (CGI) is about 37.2 mi away.

Something else? Call us any time on +1 (833) 311-3855 .

Rooms from $131/night

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